http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-438786-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_850a17186ff51f03c607cf42a534a635 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
filingDate | 1996-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cbebcb70652d57c203768ff2c075b0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7115f85ea106f5cbe799a861dc2297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_160092d767f29df05afee9be2221cc5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f39306eeb184843362ebee76f75442dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f777621e1340a55f18038e7470554b |
publicationDate | 2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-438786-B |
titleOfInvention | Novel benzothiazole derivatives |
abstract | Novel benzothiazole derivatives and their pharmaceutically acceptable salts for medical use are provided. The present invention relates to benzothiazole derivatives expressed by the following formula, in which R1 is a halogen, C1-6 alkyl, trifluoromethyl, ethyl amide, (methoxyethoxy)methoxy or -OX1, wherein X1 represents hydrogen, C1-6 alkyl or C1-6 carbonyl group; R2 is hydrogen, halogen, C1-6 alkyl, C1-6 hydroxyalkyl, trifluoromethyl, nitro, amine which can be substituted by C1-6 alkyl or C1-6 carbonyl, carboxyl which can be esterified by C1-6 alkyl, (methoxyethoxy)methoxy or -OX2, wherein X2 represents hydrogen, C1-6 alkyl, C1-6 carbonyl or C1-6 alkylcarboxyl which can be esterified by C1-6 alkyl; n, between 1 to 3, represents the number substituted by R2 in benzene ring, when n is 2 or 3, R2 may be identical or distinct, when R2 is hydrogen, R1 is a group except chloride. The compound of the present invention has such excellent pharmacological effect as to significantly decrease lipids in the blood such as cholesterol, triglycerides and low-density lipoproteins, thus useful as a novel therapeutic agent for hyperlipemia. |
priorityDate | 1995-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.