http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-438596-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1bb776b09b35d30f5ff10a3fbe311da |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_823d54caebca0c47c8116d8f12efe3b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e15a0ab95a2c9d1de22a56be239a67de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8856487ff1bcf0a9c2318d282b17923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce9717b070009f58089f53944d7c8639 |
| publicationDate | 2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-438596-B |
| titleOfInvention | Preparation of a new technetium-99m radiopharmaceutical kit for dopamine transporter imaging |
| abstract | A stable kit formulation has been developed for preparation of 99mTc-TRODAT-1 with high yield. New formulation comprises HC1 salt of TRODAT-1 to improve the stability and solubility of free TRODAT-1. Mannitol is used to stabilize the lyophilized component. Following reconstitution with 99mTc-pertechnetate and heating, 99mTc-TRODAT-1 can be obtained in a neutral solution with greater than 90% radiochemical purity determined in 1.5 hours. The shelf life of the lyophilized kit lasts at least 2 months when it was stored at 33 DEG C. Brain SPECT study on primates verifies the clinical potential of 99mTc-TRODAT-1 preparation with this novel kit formulation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2860169-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010118706-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1314456-C |
| priorityDate | 1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.