| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37555e87c88017b74fba94c8b8abbb42 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16 |
| filingDate |
1993-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b854c462abbe4cac7c4025508ff0e8ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da91557fcb462f122741d90ebfa458b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11c6626b2ba17938997e17537917afcb |
| publicationDate |
2001-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-436476-B |
| titleOfInvention |
Process for the stereoselective preparation of a β-phenylisoserine derivative and the preparation of taxane derivatives |
| abstract |
β-phenylisoserine derivatives of formula are stereoselectively prepared by the action of an N-carbonylbenzylimine of formula Ar-CH=N-CO-R on an optically active amide of a protected hydroxyacetic acid of formula followed by hydrolysis of the product obtained. In formulae (I), (II) and (III), R represents an unsubstituted or substituted phenyl radical or a radical R1-O-, Ar represents an unsubstituted or substituted aryl radical and G1 represents a hydroxyl-protecting group. The products of formula (I) are especially useful for the preparation of taxol and taxotere, which possess noteworthy antitumour properties. |
| priorityDate |
1992-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |