http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-434256-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3415cdea463c93f5a5cde1d1b07e826b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a3d835215c9c39857ece0f8a624f4fe |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate | 1996-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2001-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9da40a5d04c77cb12ef6d3c96480414d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6923011ac14dd8e1f6660ab1e3df0359 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55c0594316872d772db75f3bafc7340c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa007bd35ced203960d5228c00bc9fcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e565ac2e2bd275586ddd55c3c24bf978 |
publicationDate | 2001-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-434256-B |
titleOfInvention | Antigen non-specific glycosylation inhibiting factor derivatives |
abstract | Antigen non-specific human glycosylation inhibiting factor derivatives having the immunosuppressive activity in which a mutation was introduced for replacement, deletion and/or insertion of a part of the amino acid sequence of SEQ ID NO:1, and/or which has received a chemical modification of one or more amino acid residue(s) in the amino acid sequence of SEQ ID NO:1, wherein the mutation and the chemical modification attenuate the strength of an intermolecular association in the region, which participates in trimerization, of an antigen non-specific human glycosylation inhibiting factor having the amino acid sequence of SEQ ID NO:1; DNAs containing a base sequence encoding the amino acid sequence of the antigen non-specific human glycosylation inhibiting factor derivative; recombinant vectors containing the DNAs; prokaryotic or eukaryotic cells transformed with the DNAs; methods of producing the antigen non-specific human glycosylation inhibiting factor derivatives; pharmaceutical compositions comprising the antigen non-specific human glycosylation inhibiting factor derivative and a pharmaceutically acceptable carrier; and methods of suppressing a human immune response to an antigen are provided. |
priorityDate | 1995-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 330.