http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-419476-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-60
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58
filingDate 1998-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2001-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9fd8b03ef0fcdaa99213dc455e4c40f
publicationDate 2001-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-419476-B
titleOfInvention Preparation process of 1-chlorocarbonyl-4-piperidinopiperidine pr hydrochloride thereof
abstract The present invention provides a highly safe and easily operable process for preparing 1-chlorocarbony1-4-piperidinopiperidine or hydrochloride thereof in a high yield.Described specifically, the present invention relates to a process for preparing 1-clorocarbony1-4-piperidinopiperidine or hydrochloride thereof, which comprises reacting 4-piperidinopiperidine with a trialkylsily1 halide to obtain a 4-piperidinopiperidiny1 trialkylsily1, reacting it with a carbon dioxide gas to obtain a 4-piperidinopiperidiny1 trialkylsily1 carbamate derivative, reacting the derivative with thiony1 chloride or the like to obtain 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride and optionally treating it with a strong base.
priorityDate 1997-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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