http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-413675-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-30 |
filingDate | 1995-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2000-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff11dd5f0118bc0fa39037370e7fbfb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba2ee99931efb248c3a4cbb1160ba7de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44865291798abff8abd781f15f98987f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e545514fc230267759b09e57a2e99867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d428c95667ebe242256549624355cc9e |
publicationDate | 2000-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-413675-B |
titleOfInvention | Substituted 4-biarylbutyric or 5-blarylpentanoic acids and derivatives matrix metalloprotease inhibitors |
abstract | Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula (T)xA-B-D-E-G, wherein A and B are aryl or heteroaryl rings; each T is a substituent group; x is 0, 1, or 2; the group D represents formulas, the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formaiton, possible structures being shown in the text and claims; and the group G represents -PO3H2, -M, formulas, in which M represents -CO2H, -CON(R11)2, or -CO2R12; and R13 represents any of the side chains of the 19 noncyclic naturally occurring amino acids, and include pharmaceutically acceptable salts thereof. |
priorityDate | 1995-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 892.