| abstract |
A diamine-platinum complex represented by the formula (1), wherein R1 represents hydrogen atom, C1-5 alkyl or cyclohexyl; R2 represents hydrogen atom, C1-4 alkyl or cyclohexyl or benzyl; R3 represents hydrogen atom, C1-3 alkyl or cyclohexyl; X represents iodine or chlorine, or two X groups bind to each other to form 1, 1-cyclobutane dicarboxylate, with the proviso that R1, R2 and R3 are not hydrogen atoms at the same time. Said compounds have a high water solubility and an excellent antitumor effect. |