Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2a9fdb394126467fc0178f63a0e100b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2000-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b337bce0aeb992cc4c6727110f06352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_488c7e5e13e9eed7a25e9ae4ee4cacde |
publicationDate |
2000-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-397836-B |
titleOfInvention |
Tumour localising photosensitising compounds |
abstract |
Improved tumour localisation of polyether-substituted photosensitising compounds is given leading to their more efficient uptake into turmour cells. Lower overall doses of drug give an improved side-effect profile of the treatment especially with regard to skin photosensitisation. Compounds being polyethylene glycol derivatised, pharmaceutically acceptable tumour locating dihydro or tetrahydro porphyrins of the formulae (3) and (4) wherein R1 may be partly hydroxyl but at least one chain of formula -O-X-[CH2CH2O]m-Y wherein m = 25 to 150; the group Y may be a C1-C4 alkyl group but preferably a methyl group and the group X is of formula (5). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108715591-A |
priorityDate |
1994-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |