| abstract |
The invention relates to a compound of formula, in which R1 represents a (C2-C6)alkyl; a group -(CH2)n-G with n ranging from 0 to 5 and G representing a non-aromatic C3-C13 mono- or polycyclic hydrocarbon group; a phenyl(C1-C3)alkyl in which the phenyl group is optionally substituted with a halogen or with a (C1-C3)alkoxy; a group -(CH2)nNR2R3 in which n represents an integer from 1 to 6 and R2 and R3, which may be identical or different, represent a (C1-C3)alkyl or constitute, with the nitrogen atom to which they are attached, morpholino or piperidino ; X1, X2, X3 or X4 each independently represents a hydrogen or halogen atom, a (C1-C6)alkyl or a (C1-C3)alkoxy ; it being understood that only one from among X1, X2, X3 and X4 possibly represents a hydrogen atom ; R4 represents a group -(CH2)nCOOR5 in which n ranges from 1 to 5 and R5 represents a hydrogen atom or a (C1-C6)alkyl ; a (C1-C6)alkyl ; a group -(CH2)nOR5 in which n ranges from 1 to 5 and R5 is (C1-C6)alkyl ; a group -(CH2)n-tetrazolyl in which n ranges from 1 to 5, or R4 represents one of these groups in the form of an alkali-metal salt; Y1, Y2 and Y3 independently represent a hydrogen, a halogen, a (C1-C3)alkyl, a (C1-C3)alkoxy or trifluoromethyl; or one of the salts or solvates thereof. These compounds are CCK-receptor agonists. |