| abstract |
Novel tetrazole derivatives represented by the formula wherein n denotes an integer of 1 to 3; A is a heterocyclic residue selected from oxazolyl, thiazolyl and triazolyl, the heterocyclic residue optionally being substituted by (1) C1-5 alkyl group, (2) C6-10 aryl group optionally substituted by halogen or C1-5 alkyl group, (3) C3-7 cycloalkyl group, (4) thienyl, (5) amino group optionally substituted by C1-4 alkyl group or phenyl, (6) benzo [b] furanyl or (7) furyl; Y is a C1-5 alkylene or C2-5 alkenylene: and X is CH or N, or a pharmaceutically acceptable salt thereof, have excellent hypoglycemic and hypolipidemic activities. |