| abstract |
The object of the present invention is to provide a formulation technology comprising diphenhydramine and/or its salts, glycyrrhizic acid, its derivatives and/or their salts, allantoin and/or its derivatives, and heparin analogs In the external composition of the substance, discoloration due to storage can be suppressed, and the external composition has excellent formulation stability. Formulation of sorbitan fatty acid esters in combination with diphenhydramine and/or salts thereof, glycyrrhizic acid, derivatives thereof and/or salts thereof, allantoin and/or derivatives thereof, and heparin analogs and The composition for external use made of/or polyoxyethylene alkyl ether can suppress discoloration due to storage, and can have excellent formulation stability. |