abstract |
The present disclosure relates to fused quinazoline derivatives, their preparation methods and medical use. Specifically, the present disclosure relates to a fused quinazoline derivative represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the derivatives, and its use as a therapeutic agent, especially as SOS1 inhibitor, as well as the use thereof in the preparation of medicaments for the treatment of diseases or conditions improved by the inhibition of SOS1. |