abstract |
Specific antigen binding molecule, preparation method and pharmaceutical use thereof. Concretely, the invention relates to anti-BCMA antibody, bispecific antigen binding molecule binding BCMA and CD3 and their use. Further, the invention relates to a chimeric antibody, a humanized antibody and bispecific antigen binding molecule binding BCMA and CD3 comprising a CDR region of the anti-BCMA antibody, medicine composition thereof, and use thereof as an anti-cancer medicament or treat autoimmune diseases. In particular, the invention relates to a bispecific antigen binding nmolecule binding BCMA and CD3, and the preparation of medicaments for BCMA - mediated diseases or conditions thereof. |