| abstract |
The invention belongs to the technical field of medicine, relates to the use of fibroblast growth factor receptor inhibitors, and in particular relates to a compound represented by the general formula (I) and pharmaceutically acceptable salts and isomers thereof for the treatment of cholangiocarcinoma disease , a pharmaceutical composition comprising the same, a method for using the same for treating cholangiocarcinoma disease, its use for treating cholangiocarcinoma disease, and its use in the preparation of a medicament for treating mammalian cholangiocarcinoma disease. Each variable in the general formula is as defined in the specification. Studies have shown that the compound of general formula (I) or its pharmaceutically acceptable salts and isomers has a significant therapeutic effect on cholangiocarcinoma, and has great potential for clinical application. |