| abstract |
The present invention provides a vaccine for preventing and/or treating infection caused by human papillomavirus. The lipid particles of the present invention contain nucleic acids capable of expressing the E6 antigen and E7 antigen of human papilloma virus, and the lipid includes the cationic lipid represented by the general formula (Ia) or a pharmaceutically acceptable salt thereof. In the formula, R 1 and R 2 independently represent a C 1 -C 3 alkyl group; L 1 represents a C 17 -C 19 alkenyl group which may have one or more C 2 -C 4 alkoxy groups; L 2 represents a having one or a plurality of C 2 -C 4 alkanoyl group of C 10 -C 19 alkyl group, or may have 2 -C 4 alkanoyl group of C 10 -C 19 alkenyl group or a plurality of C; p is 3 or 4. |