Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94c0947eca5552ef3276395fa643533f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 |
filingDate |
2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4c57003bb1e668c4f1aea6784531d03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6be8fa3a609e7e0f4f528f787e75be98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b1206a23334bff3c334084a0372c1d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90eda3442fcb91926e65f8376481ea92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5267667b7c7a168b8c0d2f2aaeb462f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_173776d4099a4430578ca13ce9d75ca8 |
publicationDate |
2021-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-202122375-A |
titleOfInvention |
Method for manufacturing 1,5-benzothiazepine compound |
abstract |
The present invention provides a method for producing 1,5-benzothiazepine compounds. The method can reduce the amount of solvents used, does not repeat the purification of intermediates, and produces a suitable product with higher purity at a higher yield. Large-scale production of 1,5-benzothiazepine compounds on an industrial scale.nThe method for producing the compound of formula (I) of the present invention includes the step of reacting the compound of formula (II) with the compound of formula (III) in the presence of a compound of formula (I) to obtain the compound of formula (IV); And the step of deprotecting the compound of the above formula (IV) to obtain the compound of the formula (I). |
priorityDate |
2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |