| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d07a4ddba85ae3e35ca0a6f85dad9f6d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-7051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56977 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2020-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d73474521a79e54aa9e9604df09583f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a523e66f880e8bd4c82d816b139b8d7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0842c9ffc892213e56bfc045459a4e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3bce5298126dda938581bc4bec58816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d11bf472eda67012c0efdd57fa5543 |
| publicationDate |
2021-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-202118779-A |
| titleOfInvention |
Methods of identifying t cell receptors |
| abstract |
The present disclosure is directed to methods of identifying MHC class II-specific T cell receptors (TCRs). In certain aspects, the method comprises contacting a T cell with a complex comprising an (i) MHC class II molecule having a higher affinity for CD4 than naturally occurring MHC class II molecules and (ii) a peptide, e.g., an epitope. In certain aspects, the HLA class II molecule comprises a beta chain having one or more mutations relative to a wild-type beta chain sequence. |
| priorityDate |
2019-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |