Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b7a3d9ece0f46f57ff17f509fdffbbf |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2020-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13b425c02dbd927d0ab0ffeb6deb2b73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5ce18c3828716470317c6ef87b750f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60e26b4d1a100e6eaa9ed06d1f1f8bda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82d499d15ae65d36ea046532280f4c0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86098901029c29b6e2338179262db382 |
publicationDate |
2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-202115076-A |
titleOfInvention |
Pyrimidine five-membered nitrogen heterocyclic derivatives, a preparation method thereof and pharmaceutical use thereof |
abstract |
The disclosure relates to pyrimidine five-membered nitrogen heterocyclic derivatives, a preparation method thereof and pharmaceutical use thereof. Specifically, the disclosure relates to pyrimidine five-membered nitrogen heterocyclic derivatives represented by the general formula (II), a preparation method thereof, pharmaceutical compositions containing the same and as a therapeutic agent, particularly the use as a SHP2 inhibitor and use thereof in the preparation of a medicament for preventing and or treating tumor or cancer. The definition of each substituent of formula (II) is as defined in the specification. |
priorityDate |
2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |