| abstract |
The present invention relates to aromatic ring or aromatic heterocyclic compounds, preparation method and medical use thereof. In particular, the present invention relates to a compound of general formula (I), the preparation method thereof, the pharmaceutical composition comprising the same, and use thereof as Farnesoid X receptor (FXR) agonist. The compound and the pharmaceutical composition comprising the same can be used for the treatment and/or prevention of diseases associated with FXR activity, such as cholestasis, diabetes and its complications, non-alcoholic fatty liver (NAFLD), non-alcoholic steatohepatitis (NASH), obesity or metabolic syndrome (complicated condition of dyslipidemia, diabetes and abnormally high body mass index), and cardiovascular disease. The definition of each groups in general formula (I) is the same as that in the description. |