| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d137f8e7503ba75f6edf7cbdf54e98c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39bf0bb8b07e151d4bcead749d7dd699 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 |
| filingDate |
2020-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec3d370d8fb2a6edb7be49b6bb9da6b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_211553ae53bc8402b670c074ada4ec5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1af070dc515ed659e88208262f4f1e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_155414a6273489d95aaf7f512ac4cf8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c3235277337c212c8f6e10c20df59cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb1abd5339adf840c54c4641c649c4cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79353b9de8ce0a25f10d70fd7c63b70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d27b43479899e4f32925f4103940621
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18bb031e26f26d83806f716213b92cb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2598d6c97e60b1d8f54f12f69287353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64eb5846747fb1cecb9148dae858787
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f0b10742018ced6c19d47e15284c6aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e878603f3fa1aa80d258055ada14046 |
| publicationDate |
2021-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-202102255-A |
| titleOfInvention |
Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof |
| abstract |
A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC). |
| priorityDate |
2019-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |