http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-202045163-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e54d07fe8c2b4403b27798dc534adb05 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 |
| filingDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1df74827391a5628449477b2ab6eb383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edc47998f9f81a4f24ce0f396ebdc987 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11ce5a157f7c17192e457c0cdfd9dc96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_777d0ab6aa07f15ed4b47621dc5ee182 |
| publicationDate | 2020-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-202045163-A |
| titleOfInvention | Synthesis of 1,2,4-triazole derivatives as anti-inflammation substance and use thereof |
| abstract | Novel synthesis of 1,2,4-triazole derivatives as the anti-inflammation substance is disclosed in the present invention. An efficient green method was developed for the synthesis of multi-substituted 1,2,4-triazoles with good yields from nitrilimines including amination and heterocyclization two steps reactions. 1,2,4-triazole derivatives were observed significant anti-inflammatory effects by inhibiting NO in LPS-induced RAW 264.7 cells, which can be used to develop various inflammatory drugs for treating related diseases. |
| priorityDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.