abstract |
The present invention relates to a compound (as shown in formula I) used as an inhibitor of Src homologous region 2 protein tyrosine phosphatase 2 (SHP2), its pharmaceutical composition, preparation method, and its use in the treatment of SHP2-mediated In the disease. The compounds of the present invention play a role by participating in the regulation of multiple processes such as cell proliferation, apoptosis, migration, and angiogenesis. |