Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b2f305b78fd0f543269493582475929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_440b3059c9bcd1d85fd383f9b2ae1b40 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2304 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2315 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f149332514808ee63175951cf5609479 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a000da4a0d95ca81805cbf4167aa5ca9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5a4fb2c3689900f42c45a077d6196a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68a08bc35aa9ca8778eed914f0d1393a |
publicationDate |
2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-202031679-A |
titleOfInvention |
High-efficiency method of making genetically modified cells |
abstract |
The present invention seeks to improve the efficiency of the production method of chimeric antigen receptor (CAR) expressing cells.nThe present invention provides a method for producing mammalian genetically modified cells, which includes the following steps: a) Introducing a chimeric antigen receptor (CAR) encoding a cell population containing T cells from a mammal by a transposon method Protein polynucleotides to obtain genetically modified cell population; b) the endogenous cell population from the mammal that is ready to express the protein bound to the CAR; and c) the genetically modified cell population of step a) and step b) The endogenous cell population is co-cultured. |
priorityDate |
2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |