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filingDate 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f149332514808ee63175951cf5609479
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a000da4a0d95ca81805cbf4167aa5ca9
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publicationDate 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-202031679-A
titleOfInvention High-efficiency method of making genetically modified cells
abstract The present invention seeks to improve the efficiency of the production method of chimeric antigen receptor (CAR) expressing cells.nThe present invention provides a method for producing mammalian genetically modified cells, which includes the following steps: a) Introducing a chimeric antigen receptor (CAR) encoding a cell population containing T cells from a mammal by a transposon method Protein polynucleotides to obtain genetically modified cell population; b) the endogenous cell population from the mammal that is ready to express the protein bound to the CAR; and c) the genetically modified cell population of step a) and step b) The endogenous cell population is co-cultured.
priorityDate 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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