| abstract |
The present invention relates to a ligand-drug conjugate of exatecon analogs, a preparation method thereof and a use thereof. Specifically, the present invention relates to a ligand-drug conjugate having the structure of formula (-D), a preparation method thereof, a pharmaceutical composition comprising the same and a use thereof in the preparation of medicaments for the treatment of cancer via receptor regulation. The definition of each group of formula (-D) is as defined in the description. |