http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-202024032-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-1616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-255 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 |
| filingDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a069a71542d64368fa946de112f59091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d36493210bbfc0cff19fc17e103503d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55de811af2a271d5dfd9180e946c2995 |
| publicationDate | 2020-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-202024032-A |
| titleOfInvention | Process for the preparation of methyl 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylate |
| abstract | Herein is provided a novel process for the preparation of methyl 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylate by a Suzuki coupling of compound (3), wherein LG represents a leaving group, with an organoboron reagent: Compound (3) is obtained by activation of compound (4) with a leaving group LG, and compound (4) is obtained by alpha-arylation of methyl 5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene-2-carboxylate with 1-LG'-2,4-dichlorobenzene, wherein LG' represents a leaving group. |
| priorityDate | 2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.