| abstract |
The present invention relates to compounds, pharmaceutical compositions containing them, and methods for their preparation, and their use as TRK inhibitors. The compound is a compound represented by Formula I, or a pharmaceutically acceptable salt, prodrug, solvent compound, polymorph, isomer, and stable isotope derivative thereof. The invention also relates to the use of the compound for the treatment or prevention of related diseases mediated by TRK, such as tumors, and methods of using the same to treat the diseases. |