| abstract |
The invention relates to a method for producing amidamine compound, which has the following steps: in a first reactor, a microbial cell containing a nitrile hydratase or a microbial cell treated product thereof is contacted with a nitrile compound in an aqueous medium to obtain amidamine A reaction liquid of the compound; and reacting the reaction solution containing the amidine compound obtained in the previous step in a second reactor having a plug flow region, and the Reynolds number in the second reactor is The control becomes 5 or more and 1000 or less. |