| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9880469dc8f12dad7c3ad95c6ab31fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-453 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c46205bafe59311a3c7cc75b0853a129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_079f80094a47831d7a2bc6d2d2b229e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e37eda70f9b70c43425a99ef4f7aab2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb65d7be22e1fe69b05e58073339090 |
| publicationDate |
2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201938160-A |
| titleOfInvention |
Method for treating solid tumor with CCR2 antagonist |
| abstract |
In particular, the present invention provides a method for treating solid tumors by administering an effective amount of a chemoattractant receptor 2 (CCR2) antagonist. The present invention also provides a method for reducing the number of macrophages in the microenvironment of solid tumors, which method comprises administering an effective amount of a chemoattractant receptor 2 (CCR2) antagonist. In another aspect, the present invention further provides a method of increasing the number of CD8 + T cells in the microenvironment of a solid tumor, the method comprising administering an effective amount of a chemotactic receptor 2 (CCR2) antagonist. In some embodiments, the CCR2 antagonist has Formula I: . |
| priorityDate |
2018-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |