| abstract |
The invention provides 4- (4- (1-isopropyl-7- pendant-1,4,6,7-tetrahydrospiro [indazole-5,4'-piperidine] -1'-carbonyl) -6-methoxypyridin-2-yl) benzoic acid tris salt as crystalline anhydrous or trihydrate; and polymorphic forms, pharmaceutical compositions, dosage forms, and their use in the treatment of animals by inhibiting the carboxylation of acetyl coenzyme A The use of enzymes (acetyl-CoA carboxylase, ACC) enzymes to regulate diseases, conditions or disorders. |