abstract |
The present invention provides a cationic lipid that can be used to deliver a nucleic acid to the cytoplasm. The cationic lipid of the present invention is, for example, a compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof. [Chemical 56] [Wherein L 1 and L 2 each independently represent an alkylene group having 3 to 10 carbon atoms, and R 1 and R 2 each independently represent an alkyl group having 4 to 24 carbon atoms or an alkenyl group having 4 to 24 carbon atoms, R 3 represents an alkyl group having 1 to 3 carbon atoms, and X 1 represents a single bond or -CO-O-]. |