http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201915009-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f683349ec51134246442157fc2ca82a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate | 2017-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8756762cf91c9dcfd622c7a043f1799f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8281232f00a90b4a99295af7206aaae2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe46b878793c2e4e6ba1b36c0549b9bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d542f0a483fda52e79b3a75bea42961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f78f015e5dd4f181e21a9f9d95da1217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49dc997dc9794a6295b1a1784fa37747 |
| publicationDate | 2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201915009-A |
| titleOfInvention | Method for synthesizing ethical peptide (Etelcalcetide) or a salt thereof |
| abstract | The present invention provides a method for synthesizing Etelcalcetide or a salt thereof, the steps comprising the steps of: (a) solid phase support having an amine group at the end as a starting point of synthesis by Fmoc solid phase synthesis, and sequentially synthesizing The amino acid of the formula D in the formula (I), and after removing the Fmoc protecting group, forms a C-terminus bonded to the amine group of the solid phase support, and is N-terminally acetyl (Ac) and D -Cys and D-Arg having a side chain protecting group of fragment A: (b) removing the side chain protecting group of the D-Cys in the fragment A, forming a fragment B: (c) adding (protecting group)-L-Cys (Protecting group) -OH forms a disulfide bond with the fragment B to form a fragment C: (d) A lysate is added to the fragment C to obtain an eptikapeptide. The method for synthesizing eptikapeptide or a salt thereof of the present invention can shorten the process steps and time for preparing eptikapeptide, and provides a synthesis method with high yield and high purity. |
| priorityDate | 2017-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.