| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_747b5d1b9aa35eaf0e8131c0aef139f0 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 |
| filingDate |
2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5ea4b9d32b754422bcb02b4aa4088c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28baed5c5d9895d1b7cd8e2411f2a97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50e0eee383d68d3e4b79a3756a3fd7c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cffd2b82cb6f55664afdd2a8ea9d6984
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a92d21bf073f00292124654d74aac7a |
| publicationDate |
2019-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201910510-A |
| titleOfInvention |
Attenuated live vaccine for cold adaptation and removal of virulence factors for mucosal transmission |
| abstract |
The present invention provides pharmaceutical compositions and methods for attenuated live influenza vaccines for nasal administration using cold-adapted influenza viruses that lack virulence factors, and includes mutations that provide sufficient replication capacity for the production of vaccines. The vaccines thus produced provide significant cross-protection for non-inoculated strains. The vaccine is safe for children under 2 years of age and adults over 49 years of age. In addition, cold-adapted virulence factor-deficient influenza viruses can be adapted to provide immunity to non-influenza pathogens. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021179961-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115190911-A |
| priorityDate |
2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |