| abstract |
The object of the present invention is to provide a formulation which is expected to improve the bitterness of the organic acid salt of Vonolazan and to dissolve the organic salt of Vonarazan quickly after administration.n n n The present invention provides a preparation containing fine particles or granules, wherein the fine particles or granules contain: (1) core particles containing an organic acid salt of Vonorazan, (2) containing and forming Vono in (1) The intermediate layer of the same organic acid or salt thereof as the organic acid of the Razan salt, and (3) a coating layer containing a water-insoluble polymer. |