abstract |
The present invention relates to an anti-GITR antibody, an antigen-binding fragment thereof, and a medicinal use thereof. Further, the present invention relates to a chimeric antibody, a humanized antibody including the CDR region of the anti-GITR antibody, a pharmaceutical composition including a human anti-GITR antibody and an antigen-binding fragment thereof, and its use as an anticancer drug. In particular, the present invention relates to the use of a humanized anti-GITR antibody in the manufacture of a medicament for the treatment of a disease or condition of a GITR vector. |