Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116fa4406381fc82bb76e8657e68788a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 |
filingDate |
2018-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d94a44a4b43a22daae2bdf0f23f5b20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_976ba5ebd532f1b740dca6447d017512 |
publicationDate |
2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-201902880-A |
titleOfInvention |
Method for using a trisubstituted benzotriazole derivative as a dihydroorotate oxygenase inhibitor |
abstract |
The present invention provides methods for treating cancer in an individual and for inhibiting tumor growth, metastasis, or dihydroorotate oxygenase activity of tumors or cancer cells. Add at least one tri-substituted benzotriazole derivative of formula (I) Administered to the individual or in contact with the cancer cell. The compounds of formula (I) and their pharmaceutically acceptable salts have substituents R 1 , R 2 and R 3 , and these substituents have the meanings given in the description. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11717512-B2 |
priorityDate |
2017-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |