| abstract |
The present invention discloses an N- (azaheteroaryl) ring endofluorenamine-1-carboxamide derivative having the structure of formula (I), and a preparation method and application thereof. The definition of each substituent is as described in the specification and the scope of the patent application. Described. The compounds of the present invention can be widely used in the preparation of drugs for treating cancer, tumor, autoimmune disease, metabolic disease or metastatic disease, especially for treating ovarian cancer, pancreatic cancer, prostate cancer, breast cancer, cervical cancer, neuroglia Drugs for blastoma, multiple myeloma, metabolic disease, neurodegenerative disease, metastasis of primary tumor site, or bone metastatic cancer are expected to develop into a new generation of CSF1R inhibitor drugs. |