| abstract |
The present invention relates to the use of an enfumafungin derivative triterpenoid antifungal compound in combination with other antifungal agents such as azoles, polyenes, lipopeptides, and allylpyramine to treat fungal diseases. More specifically, the present invention relates to an antifungal combination of an enfufenal derivative triterpene and other antifungal agents such as a fungal active agent for the treatment and / or prevention of infections caused by molds. Fenjing derivative triterpenes are inhibitors of (1,3) -β-D-glucan synthesis. These other antifungal agents have antimycotic activity, including (but not limited to) voriconazole, oxa Isavuconazole, posaconazole, itraconazole, and amphotericin B. |