http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201835079-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6414cf0912e2737a41f574e3435772e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b5454abd09f216530c44daae0e81afa |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
filingDate | 2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be4c7514afcb4cb04ac1c2bfe330947d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_183cdb5b8aeb81e5a923112dd29f85ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb6861fef3c8bce49250d5281f335b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e73685003cf5a8dc71c7209c0d36f79f |
publicationDate | 2018-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201835079-A |
titleOfInvention | 6-pyrazole-[1,2,4]triazolo[4,3-α]pyridine-3-decylamine derivative, preparation method thereof and application thereof in medicine |
abstract | The invention belongs to the field of medicine, and relates to 6-pyrazole- [1,2,4] triazolo [4,3- a ] pyridine-3-amidine derivatives, a preparation method thereof and its application in medicine. Specifically, the present invention relates to a novel 6-pyrazole- [1,2,4] triazolo [4,3- a ] pyridine-3-amidine derivative represented by the general formula (I), Its preparation method and its medicinal composition containing the derivative and its use as a therapeutic agent, especially as a TGF-β receptor kinase inhibitor, and in the preparation of treatment, prevention or reduction of tumors mediated by TGF-β overexpression The use in medicine, wherein each substituent of the general formula (I) is the same as defined in the specification. |
priorityDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.