abstract |
The disclosure of the present disclosure provides an antibody agent that binds to T cell immunoglobulin and mucin-3 (TIM-3) protein. Specific immunoglobulin heavy chain polypeptides and immunoglobulin light chain polypeptide sequences are specifically provided. Related nucleic acids, vectors, compositions, and methods of treating a condition or disease (such as cancer, infectious disease, or autoimmune disease) that is responsive to TIM-3 inhibition using an anti-TIM-3 antibody agent are also provided. |