http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201822766-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b6030795999b0ece55a2735b5413921 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4743 |
filingDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a124334e1f3254d5f170c8ea346c5fe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5abd38c84e1b219e29f6dbfb09f50780 |
publicationDate | 2018-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201822766-A |
titleOfInvention | Use of a dehydrothiamine [2,3-c]quinolin-12-one derivative for the preparation of a medicament for treating non-small cell lung cancer |
abstract | One kind dehydrogenation thiamine [2,3- c] quinolin-12-one derivative (thiochromeno [2,3- c] quinolin- 12-one derivatives) of a medicament for treating non small cell lung cancer, the stripper Hydrothiamine [2,3- c ] quinolin-12-one derivatives act like HSP90 inhibitors. By simultaneously degrading EGFR and cMET proteins, they overcome EGFR-TKI resistance and poison EGFR-mutant NSCLC cells, but N19 does not Like HSP90 inhibitors, they are not cytotoxic to retinal cells. |
priorityDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.