| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6012ce2ccf64fbc34ba201c9f11ada92 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 |
| filingDate |
2017-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae7d5956d30fcd8306dbf8030ef64f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7625c43c0b346db9a3ee861456e50f32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47ab56c4bc9adb0c998e11bae29d7f36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba681f4d91b948c5ca4940425fcd4120 |
| publicationDate |
2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201819401-A |
| titleOfInvention |
Trimeric stability HIV envelope protein mutation |
| abstract |
A human immunodeficiency virus (HIV) envelope protein is provided that has mutations that stabilize the trimeric form of the envelope protein. These HIV envelope proteins have certain amino acid substitutions at specific positions in the envelope protein sequence. Compared to HIV envelope proteins that do not have one or more of the indicated amino acid substitutions, the HIV envelope proteins described herein have improved trimer formation percentage and / or improved trimer yield. Nucleic acid molecules and vectors encoding the HIV envelope proteins, and compositions containing the HIV envelope proteins, nucleic acids, and vectors are also provided. |
| priorityDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |