| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af31bb464acca74afa692b9614cf10be |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate |
2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fe22d145411528a1046ff9c86e66c30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48643c0cac34f0224f9a05aac7ec158b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8ef55539c0ab8d4c02c858251128b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f336cbb1724466e13fc1fcabde8bbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91fa78556f2cc0020f19f44ce3de0a99 |
| publicationDate |
2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201813973-A |
| titleOfInvention |
Oxidative modification improves the drug penetration of cell penetrating peptides as a drug carrier |
| abstract |
The present invention provides a cell penetrating peptide dimer obtained through oxidative modification, and the two monomers are connected by a disulfide bond. The dimer can increase the medicinal properties of the peptide by enhancing the stability of the peptide carrier, reducing the rate of its hydrolysis by the enzyme, maintaining the cell penetration ability, and increasing the binding specificity and binding power of the heparan sulfate. The modified peptide can be used as a suitable drug carrier to deliver drugs for target therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I740342-B |
| priorityDate |
2016-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |