| abstract |
The present invention provides a compound of formula I or a pharmaceutically acceptable salt, solvate or hydrate thereof Wherein ring A represents a group AI or A-II A1, A2, A3, A4 independently represent C(R4aa) or N, wherein no more than one of A1, A2, A3 and A4 represents N; A5 represents C(R4b) or N; B1, B2, B3 and B4 independently Represents C(R3) or N, wherein no more than two of B1, B2, B3 and B4 represent N; n is 1 or 2; and R1, R2, R3, R4a and R4aa and R4b are as defined in the scope of the patent application And methods of using such compounds to treat proliferative diseases, particularly cancer. |