| abstract |
The present invention relates to a method for producing NKT cell ligand Ligand pulsed human CD14 positive cells by activating NKT cells to promote NKT cell proliferation, IFN-γ production, and / or potently induce cytotoxic activity, and is specifically a feature of this method To isolate the isolated CD14-positive cells in a medium containing NKT cell ligands and GM-CSF, but not substantially IL-4. In addition, the present invention relates to a method for producing a NKT cell ligand pulsed human CD14-positive cell line. Specifically, the method is characterized in that NKT cell ligands are contained in the isolated CD14-positive cells, but GM is not substantially contained. -CSF and IL-4. The invention also relates to a cell preparation containing a NKT cell ligand pulsed human CD14 positive cell or a NKT cell ligand pulsed human CD14 positive cell line or a medicinal use thereof. |