| abstract |
The invention relates to the field of therapeutic agents. Most specifically, the present invention provides methods of producing a conditional expression vector and for therapeutic use in an animal, the vectors exhibiting one or more immunomodulators or under the control of a gene expression regulatory system in which the activating ligand is present Therapeutic protein. Such vectors can be provided via direct injection or via in vitro engineered cells, such as dendritic cells, to treat various diseases, such as neoplastic diseases, infectious diseases, ocular diseases, lysosomal storage diseases, or liver diseases. |