Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cdbdfd4180f090ad85167d0b15f954d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-33 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-01028 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c1110750da47771a96a5f8e57b5b350 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13078b29b164ce5c4d47e143f5bfac33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31765195e40db9f61a001682c583a70a |
publicationDate |
2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-201739915-A |
titleOfInvention |
Antisense oligonucleotide for splicing adjustment of mutant dopa decarboxylase gene and use method thereof |
abstract |
The present invention discloses an antisense oligonucleotide for splicing adjustment of a mutant dopa decarboxylase gene, the sequence of which is complementary to SEQ ID NO: 1, the antisense oligonucleotide can modulate the mutant dopa decarboxylase The alternative splicing point of the gene helps to develop drugs for the treatment of aromatic L-amino acid decarboxylase deficiency. The invention also discloses a method for using the above antisense oligonucleotide in vitro cells. |
priorityDate |
2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |