abstract |
Provided herein are methods for producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method of a medium comprising stem cell mobilization factors. Also provided herein are methods of inhibiting tumor cell proliferation using NK cells and/or ILC3 cells, and populations of NK cells and/or ILC3 cells produced by the three-stage method described herein, as well as treating individuals having cancer or viral infections. Methods, methods comprising administering to a subject having the cancer or viral infection a NK cell and/or ILC3 cell and a population of NK cells and/or ILC3 cells produced by the three-stage method described herein. |