| abstract |
The present invention provides a process for producing a 2-aminonicotinic acid benzyl ester derivative. In the method, as a step, a 2-aminonicotinic acid derivative represented by □ (wherein R1 is a hydrogen atom or an alkyl group of C1 to C4, and M is an alkali metal) and □ (wherein R2 is, for example, a hydrogen atom, a halogen atom, A is, for example, a nitrogen atom, X represents a halogen atom, and Y represents, for example, an oxygen atom, and the benzyl derivative is reacted in an aromatic hydrocarbon solvent in the presence of a phase transfer catalyst or a tertiary amine. . |