Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-48 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
filingDate |
2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5163f0b69255c8620863d16ec608943d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37810c19535df0f69c92d64d5be28f5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1df53e070016dbaaf8cc4de5feebad38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02d9809ef7ec691055ef389e72ba1874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c5261596416a73f292dc8128b018164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba7f139a5a3fcf127b45bbe7b450cfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f6c9d2362814675d20ae5200a91a18c |
publicationDate |
2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
TW-201726131-A |
titleOfInvention |
Macrolide derivative of macrolide lactone immunosuppressant |
abstract |
The object of the present invention is to obtain a preparation which has improved efficacy and safety compared with tacrolimus, and the blood concentration is maintained fixed without individual differences, thereby eliminating the need to control the blood dynamics (valley concentration in the blood). Amount. The present invention relates to a polymer derivative of tacrolimus which is linked to a polyethylene glycol segment of a side chain carboxyl group of a polyaspartic acid derivative and an alcoholic hydroxyl group of tacrolimus. |
priorityDate |
2016-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |