abstract |
The present invention provides mPGES-1 inhibitory activity against pain, rheumatoid arthritis, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemia A compound useful for the purpose of prevention or treatment of malignant tumors such as retinal diseases, systemic scleroderma, and/or colorectal cancer. The present invention relates to a compound of the formula [I-a], [I-b] or [I-c], or a pharmaceutically acceptable salt thereof. □[The codes in the formula are synonymous with the code numbers described in the specification. ] |